Overview

The pharmacokinetics department mainly conducts pharmacokinetic tests of large and small molecule drugs, ADC drugs, cell therapy drugs, gene therapy drugs, endogenous drugs, etc., including in vivo and in vitro ADME studies and bioanalysis. The animal species involved include monkeys, dogs, mice, rats, rabbits, mini pigs, etc. High-standard large and small molecule bioanalysis platform provides customers with high-quality and reliable data.

Service Content

In vivo ADME test
  • Single-dose and multiple-dose pharmacokinetic tests
  • Bioavailability test
  • Tissue distribution test
  • Fecal and urine excretion test
  • Bile duct intubation surgery, drug bile excretion test
  • PK/PD studies
  • Bioequivalence studies of generic drugs
  • Identification of metabolites in vivo (blood, excreta)
  • Phoenix WinNonlin Pharmacokinetic Parameter Statistics
In vitro ADME test
  • Whole blood plasma ratio
  • Plasma protein binding rate
  • Liver microsomal metabolic stability
  • Study on liver microsomal metabolite products
  • Enzyme inhibition test
  • Enzyme induction test
  • Caco-2 model, etc.
Bioanalysis
  • LC-MS/MS, ELISA, PCR, HPLC-UV, flow cytometry, LC-Qtof, etc.
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